Toxicology of Solvents

Edited by M. McParland and N. Bates, National Poisons Information Service (London Centre)

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Health and safety have become priority issues in industries across the world. Cases of neglect have cost companies dearly. This book reviews the evidence on the effects of exposure to common industrial solvents.

Solvents have been the cause of occupational health problems for many years. Workers have been exposed through skin contact, by breathing in vapours, by splashes in the eye and, in extreme cases, by ingestion. This book examines the clinical consequences of exposure to different solvents, particularly in the workplace.

The authors have examined material from key medical and toxicological libraries, books, databases and their own case studies, to find the key effects of solvent exposure. They have gone back to original case reports to verify facts. The information is summarised here in ordered sections, including cancer causing activity, skin and eye exposure effects, inhalation effects, reproductive effects and potential genetic effects. Both acute (short-term) and chronic (long-term) exposures are reviewed. Glycol ethers and esters are covered in one chapter, other common solvents are reviewed in individual chapters.

A very useful section on first aid is included, with precautions to be taken to avoid rescuers being affected.

Medical professionals will find useful information about antidotes, tests for exposure, and hospital management of affected patients.

A glossary of medical terms is included to assist non-medical readers in understanding the text.

Key features

  • Chapters divided into concise sections
  • Useful summary at the start of each chapter
  • Synonyms and identification numbers to facilitate solvent identification
  • Physical and chemical properties
  • Occupational exposure limits
  • Biomonitoring
  • Toxicology
  • Hospital management
  • Antidotes
  • Very well referenced
  • Glossary of medical terms
  • Useful list of medical abbreviations and acronyms
  • Index includes CAS, EINECS and RTECS numbers

    About the editors
    The Medical Toxicology Unit at Guys and St Thomas Hospital in London is one of the largest specialist toxicology units in the world, providing information about poisoning to health professionals via a 24 hour telephone service. The National Poisons Information Service (London) has been operating for over 30 years and is one of the busiest in the world, handling the majority of the 200,000 calls made each year in the UK.

    All contributors are Poisons Information Specialists at the Medical Toxicology Unit, with extensive experience in advising the UK National Health Service on the consequences of chemical accidents and chemical exposures.

  • Introduction
  • First aid
  • Acetone
  • Benzene
  • Carbon disulphide
  • Carbon tetrachloride
  • Chloroform
  • Diacetone alcohol
  • Diisobutyl ketone
  • Dimethylformamide (DMF)
  • Ethanol
  • Ethyl amyl ketone
  • Glycol ethers and esters
  • Hexane/n-hexane
  • Isopropanol
  • Methanol
  • Methylene chloride
  • Methyl n-butyl ketone (MnBK)
  • Methyl ethyl ketone (MEK)
  • Methyl isobutyl ketone (MIBK)
  • N-methyl-2-pyrrolidone (NMP)
  • Tetrachloroethylene
  • Toluene
  • 1,1,1-Trichloroethane (1,1,1-TCE)
  • Trichloroethylene
  • White spirit
  • Xylene
  • Abbreviations and Acronyms
  • Glossary
  • Index

  • ISBN:
    978-1-85957-296-2
    Pages:
    400
    Publisher:
    Rapra Technology, 2002
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